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Custom Genome Editing
Need to generate mutant cell lines but too busy to do it yourself? ALSTEM offers complete genome editing services according to your specifications to help you accelerate your research. Empowered by CRISPR/Cas9 technology, our experts can generate genome edited cell lines carrying permanent knock-out, conditional knock-out, point mutation, and/or insertion to meet your needs.
Highlighted features of our genome editing service includes
Diverse and personalized editing services with high standards: We provide service following your specifications to address your unique goals. Our experts have extensive experience in various types of editing, including permanent knock-out, conditional knock-out, point mutation, and insertion.
Complete product pipeline: We design and clone your gRNA & HR donor plasmid, as well as generate stable single clonal cell lines for you. The turnaround time is ~2 to 5 months.
Transparent manufacture and convenient communication: We provide timely and final project report to keep you updated and our scientists are always ready when you have questions.
Comprehensive quality control: We validate your CRIPSR cell lines with Sanger sequencing, as well as NGS if you prefer.
Ready to use product: We provide 2 vials of cells at 0.5~1 X 106 cells/vial for each cell line we generate for you.
Please CONTACT US to discuss your gene editing project or fill in the form below and send it to us.
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Publications
Bertholet, AM., et al. H transport is an integral function of the mitochondrial ADP/ATP carrier. Nature (2019). 571, p515–520
Diggins, NL., et al. α5β1 integrin trafficking and Rac activation are regulated by APPL1 in a Rab5-dependent manner to inhibit cell migration. Journal of Cell Science (2018) 131, jcs207019. doi:10.1242/jcs.207019
Shahid, M., et al. Centromere protein F (CENPF), a microtubule binding protein, modulates cancer metabolism by regulating pyruvate kinase M2 phosphorylation signaling. Cell Cycle (2018). 17, 24, p2802–2818
Wu, M., et al. Conditional gene knockout and reconstitution in human iPSCs with aninducible Cas9 system. Stem Cell Research (2018). 29, p6-14
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We only use original parts or parts of equivalent quality. We make sure you get the best quality available on the market at the best price. All our interventions are guaranteed for a period of one year.
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We only use original parts or parts of equivalent quality. We make sure you get the best quality available on the market at the best price. All our interventions are guaranteed for a period of one year.
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